Clinical & Chronic Disease Research
The Department of Family Medicine identifies factors associated with increased risk of developing chronic conditions and best practices for management of chronic disease symptoms. Research projects involve development of effective prevention and treatment programs to promote healthy lifestyles.
Clinical & Chronic Disease Research
Principal Investigator: Steffani Bailey, PhD
The study examines
the implementation of Stage 1 Meaningful Use criteria and identifies
facilitators and barriers to assessing and treating smoking in
Federally-Qualified Health Centers (FQHCs). This research will inform the development of a primary care-based
smoking cessation intervention that utilizes health information technology. It will use quantitative data from OCHIN, a
multiple-facility, linked EHR provider, and qualitative data from clinic
observations and interviews with health care providers and patients.
Principal Investigator: Timothy Burdick, MD, MS
STOP CRC is a
cluster-randomized pragmatic study designed to increase rates of CRC screening
in safety-net primary care practices. The overall goal is to increase CRC
screening rates in large numbers of diverse patients by devising and testing an
intervention that uses a low-cost fecal test. This study is in partnership with
26 FQHC clinics, all of which use the EPIC electronic medical record (EMR)
provided by OCHIN. This project promotes the use of
fecal immunochemical testing (FIT) for colorectal cancer screening, as it has
been shown to be an effective population-based strategy for increasing CRC
screening rates.
Principal Investigator: Richard Deyo, MD, MPH
This project will
examine patients with chronic pain who do or do not use acupuncture services
for their care. It seeks to identify differences that may predispose people to
use acupuncture, and differences in outcomes that may result. The project will
make use of electronic medical records in the Kaiser Permanente Northwest
healthcare system to measure healthcare utilization;a prospective cohort study
to measure patient outcomes;and qualitative methods to understand the decision-making
process.
Principal Investigator: Richard Deyo, MD, MPH
The overarching goal of this research is to help providers
improve the care of complex patients requesting controlled prescription
medication. Specifically, the study examines the potential of a statewide
prescription monitoring program (PMP) to help providers assess whether a given
patient has a legitimate pain need, an addiction, or intent to divert or misuse
controlled substances.
Principal Investigator: Richard Deyo, MD, MPH
This supplement complements the initial project, and has
three additional goals: 1) develop a metric for the potential risk associated
with the prescriptions that a patient is receiving, as a function of time;2)
develop a metric for the degree of PDMP usage by prescribers, as a function of
time;and 3) analyze the relationship between patient potential prescription
risk and prescriber PDMP usage, to test the hypothesis that higher PDMP usage
is related to lower patient prescription risk. These metrics would be calculated based on data that has been collected
by the Oregon PDMP since its inception in 2011.
Principal Investigator: Richard Deyo, MD, MPH
This proposal will extend work on a multisite randomized
trial of epidural steroid injections for lumbar spinal stenosis. It will take
advantage of new study sites for recruitment and data collection.
Principal Investigator: Richard Deyo, MD, MPH
This proposal
develops methods for studying the implementation of a new strategy for
reporting imaging results for the lumbar spine. The plan is to provide
epidemiologic data regarding the prevalence of certain findings in normal
adults, with the goal of reducing unnecessary patient or primary physician
alarm. The ultimate goal is to reduce unnecessary further testing or treatment
that may result from misunderstanding of the imaging results.
Principal Investigator: Richard Deyo, MD, MPH
The aims of this research are: 1) Conducting a cluster
(clinic) randomized pragmatic clinical trial in 40 primary care clinics across
the three KP health plan settings (Hawaii, Northwest, Georgia) to compare the
effects of the multidisciplinary biopsychosocial intervention to usual care on
patients' pain symptoms, pain-related functioning, and satisfaction with health
care services;patients' use of health care services including receipt of
opiate medication, and the cost of the program and economic impact of the
intervention. As cost considerations will be important for the translatability
of this project, articulating the cost impact for health plans will be an
important aspect of the dissemination. 2) Conducting process and implementation evaluations to understand,
describe, explain, and enhance intervention Reach (to diverse patients),
Effectiveness, Adoption, Implementation, and Maintenance. 3) Creating,
refining, and disseminating an implementation guide for the collaborative care
pain intervention based on findings from Aims 1 &2 and perspectives from
key informant interviews of administrators and staff at federally funded safety
net clinics that may serve as future dissemination-implementation sites.
Principal Investigator: Melinda Davis, PhD
The overarching goal of this application is to refine and
evaluate a "PCOR Coaching Model" to support CEnR on health and health systems
in rural settings. The goals for this
study are: 1) conduct a systematic review of approaches and evaluation
strategies for engaging rural populations in the conduct and translation of
research;2) develop a pragmatic, rapid cycle "PCOR Coaching Model" to
strengthen the implementation and evaluation of regional CCO transformation
initiatives;and 3) examine community-based partner knowledge, confidence, and
trust in collaborative research partnerships following implementation of the
PCOR Coaching Model.
The rationale for this project is
that these risk factors can be prospectively utilized in the form of a
prediction rule to guide prudent empiric antibiotic selection and thereby
reduce the evolutionary selective pressures that lead to increased multi-drug
resistant bacteria. Two specific aims will be pursued:
1) Develop and validate a prediction rule to guide empiric antibiotic
prescribing in adult female patients with uncomplicated urinary tract infection
by identifying patients at higher risk of infection due to TMP/SMX-resistant
Enterobacteriaceae and 2) Establish the feasibility of clinical use of the
prediction rule by assessing prospectively evaluating patient safety and
scientific validity.
Principal Investigator: Patty Carney, PhD
To evaluate the accuracy of dermatopathology interpretation,
emphasizing the classification of atypical and malignant lesions, where
previous studies reveal a concerning degree of diagnostic errors.
Principal Investigator: Miguel Marino, PhD
This project
evaluates an innovative workplace intervention designed to reduce work-family
conflict on the health, particularly cardio metabolic and sleep health, of
direct patient-care employees in the long-term health care industry. This
intervention is designed to decrease work-family conflict for employees, but
has the potential of increasing the organizational support for the work-family
needs of mid-level managers - those supervisors in the trenches who deal with
the day-to-day work life and supervision of employees - leading to improved
health of these managers.
Principal Investigator: Richard Deyo, MD, MPH
The proposed aims
include augmenting Spine Surgical Care and Outcomes Assessment Program (Spine
SCOAP) data with the addition of surveys related to personality traits, mental
health and relationships, and adding standardized evaluations of preoperative
radiographic images used in the course of clinical care. Specifically, among
patients with degenerative disc disease (DDD) undergoing fusion, aims are to
determine patient characteristics associated with non-response and determine
radiographic features at baseline that are associated with non-response. The findings of this study will ultimately be
used to develop predictive models that can be efficiently tested across
Washington State hospitals.