Cosmetic Fillers

Cosmetic FillersThe aging process and other environmental factors like sunlight can cause your skin to lose structure and volume, creating unwanted facial wrinkles and folds, such as those parentheses lines around your nose and mouth. Sagging skin can sometimes be an issue of volume loss that occurs with age, but filler substances replace that lost volume, providing immediate results. 

Restylane®, Perlane®, JUVÉDERM® XC, RADIESSE® and Sculptra® are injectable dermal fillers that can restore youthful fullness to your face, lips and contours, or soften facial creases and wrinkles. While these treatments aren't permanent, there are options that can last up to two years. 

During your consultation, your provider will work with you to choose the treatment that will work the best for you. There are two different general subtypes of filler substances. One type is a liquid or gel substance such as hyaluronic acid. These gels fill in the space to restore fullness that is lost as we age. The results are immediate. The second subtype includes collagen replacers that help restore the underlying structure of the skin. This type usually requires a series of treatments and results develop over time, but can last up to two years.

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Restylane® works immediately by adding volume to smooth away wrinkles. Its effects usually last six to nine months and can be used on any area of the face, including the lips. It is a gel formulation of hyaluronic acid that adds fullness similar to your body’s own hyaluronic acid.


Non-surgical Cosmetic Fillers at OHSUJust like Restylane®, Perlane® adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth. 

Like like Restylane®, Perlane® is a clear gel formulation of hyaluronic acid. What makes Perlane® different is the average size of the particles and the depth of the injection. On average, the gel particles in Perlane® are larger than those in Restylane, which makes Perlane® a good choice for wrinkles that benefit from a deeper injection into the skin.


JUVÉDERM® XC is a gel filler that instantly smoothes away wrinkles around any area of the face, including the lips. It usually lasts six – nine months and can be used on any area of the face, including the lips. JUVÉDERM® XC is infused with lidocaine to improve comfort during treatment.


RADIESSE® is filler that can last up to one year. In addition to the initial results, it also causes collagen stimulation in the treated areas so that with subsequent treatments the filler may last longer. RADIESSE® is suitable for any area of the face, except for the lips.


Sculptra® is most often used as a volumizer, as it provides a good solution for people who have lost volume in their cheeks. Sculptra relies almost exclusively on the body's collagen production to cause a more global revolumization of the facial structure and the results develop gradually over the first six months. It is a longer lasting filler, though, lasting anywhere from one to two years.