The heart valve clinical trials team is interested in seeing how exciting new heart valves and drugs can help to improve the outcomes and quality of life for those living with the heart valve diseases.

Feel free to call or e-mail the Knight Cardiovascular Institute research team at 503-418-1964 or by emailing heartresearch@ohsu.edu. You will then be forwarded to the appropriate research team member who will be able to see if you qualify for any of the clinical trials being offered at OHSU. 

You can also find all the of heart failure clinical trials, that are currently enrolling patients, below.

Clinical Trial Name	Principal Investigator	Sub Investigators	Protocol Number
ACTIVE: Annular Reduction for Transcatheter Treatment of Insufficient Mitral Valve: A prospective multi-center, randomized, controlled pivotal trial to assess transcatheter mitral valve repair with Edwards Cardioband System and guideline directed medical therapy (GDMT) compared to GDMT alone in patients with functional mitral regurgitation (FMR) and heart failure.	Firas Zahr, MD	Cristina Fuss, MD / Jaishankar Raman, MD, PhD, FRACS  / Howard Song, MD, PhD / Scott Chadderdon, MD	IRB00017653
APOLLO: Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in Patients with Severe Symptomatic Mitral Regurgitation - APOLLO Trial	Firas Zahr, MD / Howard Song, MD, PhD	Albert Camacho, MD / Cristina Fuss, MD / Jaishankar Raman, MD, PhD, FRACS / Scott Chadderdon, MD / Stephen Heitner, MD	IRB00017730
COAPT-CAS: Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional MR (COAPT) Continuing Access Study	Firas Zahr, MD	Albert Camacho, MD / Frederick Tibayan, MD / Howard Song, MD, PhD / Jaishankar Raman, MD, PhD, FRACS / Katherine Rajotte, PA-C / Scott Chadderdon, MD / Stephen Heitner, MD	IRB00017739
TAVR Low Risk: Transcatheter Aortic Valve Replacement (TAVR) in Patients with the Medtronic Transcatheter Aortic Valve Replacement System (TAVR) in Patients at Low Risk for Surgical Aortic Valve Replacement (SAVR)	Firas Zahr, MD / Howard Song, MD, PhD	Albert Camacho, MD / Cristina Fuss, MD / Katherine Rajotte, PA-C / Frederick Tibayan, MD / Jaishankar Raman, MD, PhD, FRACS / Stephen Heitner, MD	IRB00015782
TAVR UNLOAD: Transcatheter Aortic Valve Replacement to Unload the LEft Ventricle in Patients with Advanced Heart Failure: A Randomized Trial (TAVR UNLOAD)	Firas Zahr, MD / Howard Song, MD, PhD	Albert Camacho, MD / Cristina Fuss, MD / Jaishankar Raman, MD, PhD, FRACS / Katherine Rajotte, PA-C / Scott Chadderdon, MD	IRB00017224