OCTRI Pilot Project Awards June 2010

In 2009, OCTRI released a series of targeted funding opportunities in areas like rare disease, T1 research, and joint projects with partner organizations. In previous years, OCTRI awarded traditional pilot projects open to any clinical or translational research project as well as career development and child health pilot projects. The target areas were identified based on OCTRI priorities and opportunities to leverage resources with strategic partners like the Kaiser Permanente Center for Health Research, Pacific Northwest National Laboratory, and the Oregon National Primate Research Center.

KPCHR-OHSU Joint Projects

LeBlanc, Erin, MD, MPH, Investigator, KPCHR

"The role of Vitamin D in menopause: Relationship to menopausal symptoms and body composition" Abstract

Co-Investigators: Teresa Hillier, MD MS, Kaiser Permanente Center for Health Research; Heidi Nelson MD MPH, OHSU; Jonathan Purnell, MD, OHSU; and Nancy Perrin, PhD, Kaiser Permanente Center for Health Research

McEvoy, Cindy, MD, MCR (NFR), Dept. of Pediatrics, OHSU

"Pregnancy Weight Gain in Obese Mothers and Bronchodilator Use in Their Children" Abstract

Co-Investigators: Victor Stevens, PhD, Kaiser Permanente Center for Health Research; Kelvin MacDonald, MD RRT, OHSU; and Kim Vesco, MD, Kaiser Permanente Center for Health Research

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T1 Translational Research

Adamus, Grazyna, PhD, MS, Dept. of Opthalmology, OHSU 

"Immunotherapy with Recombinant T-cell Receptor Ligand (RTL) for Retinal Degeneration" Abstract 

Co-Investigator: Shaomei Wang, MD PhD, OHSU 

Soumyanath, Amala, PhD, Dept. of Neurology, OHSU

"Piperine and melanoma -a crucial issue for future clinical studies" Abstract 

Co-Investigators: Philippe Thuillier, PhD, OSHU; and Steven Jacques, PhD, OHSU

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Rare Disease Research

Kruer, Michael, MD, Fellow, Dept. of Pediatrics, OHSU

"Deriving novel gene discovery from families with multiple members affected by Connecting clinical findings to pathophysiology in neurodegeneration with brain iron accumulation (NBIA)" Abstract 

Co-Investigators: Susan Hayflick, MD, OHSU; and Wei-Hong Xiong, PhD MS, OHSU

Smith, Stephen, MD, Dept of Medicine, OHSU

"Calcium-sensing receptor- a novel target in rare forms of epilepsy" Abstract

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Proteomics Collaborations

with Pacific Northwest National Laboratory (PNNL)

Carter, Nicola S., PhD, Dept. of Biochemistry & Molecular Biology 

"Comparative Proteomics to Define Adaptations to Purine Stress in Leishmania" Abstract 

Co-Investigators: Scott Landfear, PhD, OHSU; Buddy Ullman, PhD, OHSU; and Phillip Yates, PhD, OHSU

Gillespie, Peter, PhD, Oregon Hearing Research Center, OHSU

"Identification of Deafness-Causing Mutations Using Proteomics-Identified Candidates" Abstract

Co-Investigators: Richard J. Smith, MD, University of Iowa; and Ulrich Müller, PhD, Scripps Research Institute

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OCTRI-ONPRC Collaborations

Johnstone, Brian, PhD, Director of Research, Dept. of Orthopaedics, OHSU 

"Chondrogenesis of rhesus macaque SCNT-ES and iPS cells in bioresponsive hydrogels" Abstract 

Co-Investigator: Shoukhrat Mitalipov, PhD, OHSU

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Investigations into the Ethical Conduct of Research

Misra, Sahana, MD, Dept. of Psychiatry, OHSU; Psychiatrist, Portland VA Medical Center

"Research Consent Capacity in Individuals with and without Traumatic Brain Injury (TBI)" Abstract

Co-Investigators: Elizabeth Goy, PhD, OHSU; Linda Ganzini, MD MPH, OHSU; and Daniel Storzbach, PhD, OHSU & PVAMC

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Biostatistical Methodologies Research

Awarded November 2009

Chen, Yiyi, PhD, Dept. of Public Health & Preventative Medicine, OHSU

The Use of Testing Confidence Value for Transitional Decisions of Single-Arm Phase II Oncology Trials " Abstract

Co-Investigators: Motomi Mori, PhD, OHSU; Tomasz M. Beer, MD, OHSU

Nguyen, Thuan, MD, PhD, Dept. of Pediatrics and Dept. of Public Health and Preventative Medicine (joint appointment), OHSU

"Fence Methods in Genetic Applications" Abstract

Co-Investigators: Robert Klein, MD, PhD, OHSU; John Belknap, PhD, OHSU; Jiming Jiang, PhD, OHSU

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